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Article

A novel locus on proximal chromosome 18 associated with agenesis of the corpus callosum in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2010

Mizuno Seiya, Mizobuchi Atsushi, Iseki Hiroyoshi, Iijima Saori, Matsuda Yoichi, Kunita Satoshi, Sugiyama Fumihiro, Yagami Ken-ichi

Abstract excerpt

Agenesis of the corpus callosum (ACC) is a congenital abnormality of the brain structure. We have produced transgenic mice expressing both reverse tetracycline-controlled transactivator (rtTA) and transcriptional silencer (tTS) ubiquitously. Although the transgene products do not affect development of the mouse brain, one of the founder lines, TAS, showed ACC, suggesting transgenic disruption of endogenous...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20967545
DOI: 10.1007/s00335-010-9292-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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