Article
Prevalence of the JAK2-V617F mutation in Taiwanese patients with chronic myeloproliferative disorders.
Internal medicine journal - 1 Jun 2008
Lieu C-H, Wu H-S, Hon Y-C, Tsai W-H, Yang C-F, Wang C-C, Lin Y-C, Shih C-H, Hsu H-C
Abstract excerpt
BACKGROUND: The Janus kinase-2 (JAK-2) V617F mutation has been recently reported in patients with myeloproliferative disorders (MPD), which is believed to underlie growth factor hypersensitivity displayed by haematopoietic progenitors in these disorders. However, its frequency has been rarely determined in Taiwanese patients. METHODS: The frequency of JAK2-V617F mutation in patients with polycythaemia vera,...
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