Article
Clinical applications of molecular haematology: JAK2 in myeloproliferative disorders.
The Journal of the Association of Physicians of India - 1 Jul 2007
Agarwal M B
Abstract excerpt
Molecular markers are helpful in diagnosis, prognosis and management of haematological malignancies. Recently, a single point mutation in the Janus Kinase 2 (JAK2) gene in the Philadelphia-negative myeloproliferative disorders, including polycythemia vera (over 95%), essential thrombocythemia (50%) and primary myelofibrosis (50%) was identified by several groups. This mutation is now considered to have a...
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