Article
Management updates for women with a BRCA1 or BRCA2 mutation.
Molecular diagnosis & therapy - 1 Jan 2007
Nusbaum Rachel, Isaacs Claudine
Abstract excerpt
In most cases of families with breast and ovarian cancer, the pattern of cancers in the family can be attributed to mutations in the BRCA1 and BRCA2 genes. Genetic testing for these cancer susceptibility genes typically takes place in the context of comprehensive genetic counseling. Strategies have been developed for the medical management of women at high risk of developing breast cancer, including options for...
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