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Article

Nek10 mediates G2/M cell cycle arrest and MEK autoactivation in response to UV irradiation.

Molecular and cellular biology - 1 Jan 2011

Moniz Larissa S, Stambolic Vuk

Abstract excerpt

Appropriate cell cycle checkpoint control is essential for the maintenance of cell and organismal homeostasis. Members of the Nek (NIMA-related kinase) family of serine/threonine protein kinases have been implicated in the regulation of various aspects of the cell cycle. We explored the cellular functions of Nek10, a novel member of the Nek family, and demonstrate a role for Nek10 in the cellular UV response....

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Source

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Identifiers

PMID: 20956560
DOI: 10.1128/MCB.00648-10
PMCID: PMC3019845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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