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Mesenchymal Stromal Cells: A New Tool against Graft-versus-Host Disease?

29 Sept 2011

Abstract excerpt

Mesenchymal stromal cells (MSCs) represent a heterogeneous subset of multipotent cells that can be isolated from several tissues including bone marrow and fat. MSCs exhibit immunomodulatory and anti-inflammatory properties that prompted their clinical use as prevention and/or treatment for severe graft-versus-host disease (GVHD). Although a number of phase I-II studies have suggested that MSC infusion was safe...

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PMID: 21963621
DOI: 10.1016/j.bbmt.2011.09.003

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