Article
The Role of Pneumolysin in Ocular Infections with<i>Streptococcus Pneumoniae</i>
1 Jan 1990
Abstract excerpt
Pneumolysin, a cytolytic protein produced by Streptococcus pneumoniae, has many properties which suggest it may be an important virulence factor in pneumococcal ocular infections. To directly test this possibility, we have constructed pneumolysin-negative strains of S. pneumoniae and compared their virulence with that of the wild type in a rabbit model of intracorneal infection. A pneumolysin-negative strain...
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