Upper and Lower Respiratory Tract Infection by<i>Streptococcus pneumoniae</i>Is Affected by Pneumolysin Deficiency and Differences in Capsule Type

Abstract excerpt

Pneumococci frequently colonize the upper respiratory tract, and these pneumococci are believed to act as a reservoir for infection of the lower respiratory tract and bacteremia. We investigated how the pneumococcal toxin pneumolysin affects the capacity of pneumococci to infect the upper and lower respiratory tract of the mouse. Wild-type Streptococcus pneumoniae serotype 2 and 3 strains, a serotype 2...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Share to Pneumocystis jirovecii pneumonia detection and treatment