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Article

Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men.

Human immunology - 1 Jan 2011

Rantala Aino, Lajunen Taina, Juvonen Raija, Silvennoinen-Kassinen Sylvi, Peitso Ari, Vainio Olli, Saikku Pekka, Leinonen Maija

Abstract excerpt

Interleukin-1 (IL-6) is an important mediator of inflammatory response in the respiratory tract during an infection, and the action of IL-6 is mediated by an IL-6 receptor. Several polymorphisms in the IL-6 and IL-6R genes have been associated with different inflammatory disease states. We studied the association between 2 IL-6 (IL6A and IL6B) and 5 IL-6R gene polymorphisms (IL6R1 to IL6R5) and respiratory...

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Identifiers

PMID: 20951753
DOI: 10.1016/j.humimm.2010.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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