Article
Lack of association between cellular repressor of E1A-stimulated genes (CREG) [corrected] polymorphisms and coronary artery disease in the Han population of North China.
Clinica chimica acta; international journal of clinical chemistry - 30 Jan 2011
Wang Tao, Zhang Mingxiang, Han Yaling, Zhang Xiaolin, Yan Chenghui, Liang Zhenyang, Sun Ying, Kang Jian
Abstract excerpt
BACKGROUND: Phenotypic switching of smooth muscle cells (SMCs) plays a critical role in the pathogenesis of atherosclerotic lesions such as coronary artery disease (CAD). Accumulating evidence demonstrates that a cellular repressor of E1A-stimulated genes (CREG) plays a role in the maintenance of the mature phenotype of vascular SMCs. We assessed the possible association between CREG and CAD in the Han population...
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