Article
MicroRNA-31 controls phenotypic modulation of human vascular smooth muscle cells by regulating its target gene cellular repressor of E1A-stimulated genes.
Experimental cell research - 1 May 2013
Wang Jie, Yan Cheng-Hui, Li Yang, Xu Kai, Tian Xiao-Xiang, Peng Cheng-Fei, Tao Jie, Sun Ming-Yu, Han Ya-Ling
Abstract excerpt
Phenotypic modulation of vascular smooth muscle cells (VSMCs) plays a critical role in the pathogenesis of a variety of proliferative vascular diseases. The cellular repressor of E1A-stimulated genes (CREG) has been shown to play an important role in phenotypic modulation of VSMCs. However, the mechanism regulating CREG upstream signaling remains unclear. MicroRNAs (miRNAs) have recently been found to play a...
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