Article
Glatiramer acetate (GA, Copolymer-1) an hypothetical treatment option for Rett syndrome.
Medical hypotheses - 1 Feb 2011
Ben-Zeev B, Aharoni R, Nissenkorn A, Arnon R
Abstract excerpt
Rett syndrome (RTT) is an X-linked dominant postnatal severe and disabling neurodevelopmental disorder which is the second most common cause for genetic mental retardation in girls and the first pervasive disorder with a known genetic basis. The syndrome is primarily caused by mutations in the Methyl CpG binding protein 2 (MECP2) gene on Xq28. Its protein product MeCP2 acts as a transcriptional repressor or...
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