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Article

Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.

PLoS computational biology - 7 Oct 2010

Gnanakaran S, Daniels Marcus G, Bhattacharya Tanmoy, Lapedes Alan S, Sethi Anurag, Li Ming, Tang Haili, Greene Kelli, Gao Hongmei, Haynes Barton F, Cohen Myron S, Shaw George M, Seaman Michael S, Kumar Amit, Gao Feng, Montefiori David C, Korber Bette

Abstract excerpt

A steady increase in knowledge of the molecular and antigenic structure of the gp120 and gp41 HIV-1 envelope glycoproteins (Env) is yielding important new insights for vaccine design, but it has been difficult to translate this information to an immunogen that elicits broadly neutralizing antibod...

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Source

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Identifiers

PMID: 20949103
DOI: 10.1371/journal.pcbi.1000955
PMCID: PMC2951345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20949103-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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