Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Large-scale screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease.

Human molecular genetics - 1 Jan 2011

Lesage Suzanne, Anheim Mathieu, Condroyer Christel, Pollak Pierre, Durif Franck, Dupuits Céline, Viallet François, Lohmann Ebba, Corvol Jean-Christophe, Honoré Aurélie, Rivaud Sophie, Vidailhet Marie, Dürr Alexandra, Brice Alexis

Abstract excerpt

Pathogenic variants in the glucocerebrosidase gene (GBA) encoding the enzyme deficient in Gaucher's disease (GD) are associated with Parkinson's disease (PD). To investigate the sequence variants, their association with PD and the related phenotypes in a large cohort of European, mostly French, patients and controls, we sequenced all exons of GBA in 786 PD patients from 525 unrelated multiplex families, 605...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gaucher Disease

Share to Genomic Structural Variation

Share to Glucosylceramidase

Share to Parkinson Disease

Share to Risk Factors

Share to White People

Source

Identifiers

PMID: 20947659
DOI: 10.1093/hmg/ddq454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Large-scale screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease.PMID 20947659Read ↗

Complete screening for glucocerebrosidase mutations in Parkinson disease patients from Greece.Semantic proximity Read ↗

Analysis of the glucocerebrosidase gene in Parkinson's disease.Semantic proximity Read ↗

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease.Semantic proximity Read ↗

Association Between Glucocerebrosidase Mutations and Parkinson's Disease in IrelandSemantic proximity Read ↗

Mutations in glucocerebrosidase are a major genetic risk factor for Parkinson's disease and increase susceptibility to dementia in a Flanders-Belgian cohort.Semantic proximity Read ↗

A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.Semantic proximity Read ↗

The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease.Semantic proximity Read ↗

Glucocerebrosidase mutations in primary parkinsonism.Semantic proximity Read ↗

Mutations in the glucocerebrosidase gene are responsible for Chinese patients with Parkinson's disease.Semantic proximity Read ↗

Strong association between glucocerebrosidase mutations and Parkinson's disease in Sweden.Semantic proximity Read ↗

GBA Variants Influence Motor and Non-Motor Features of Parkinson's Disease.Semantic proximity Read ↗

Glucocerebrosidase mutations in a Serbian Parkinson's disease population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.