A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.

doi:10.1002/mds.28112

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Article

A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.

Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2020

den Heijer Jonas M, Cullen Valerie C, Quadri Marialuisa, Schmitz Arnoud, Hilt Dana C, Lansbury Peter, Berendse Henk W, van de Berg Wilma D J, de Bie Rob M A, Boertien Jeffrey M, Boon Agnita J W, Contarino M Fiorella, van Hilten Jacobus J, Hoff Jorrit I, van Mierlo Tom, Munts Alex G, van der Plas Anne A, Ponsen Mirthe M, Baas Frank, Majoor-Krakauer Danielle, Bonifati Vincenzo, van Laar Teus, Groeneveld Geert J

Abstract excerpt

BACKGROUND: The most common genetic risk factor for Parkinson's disease known is a damaging variant in the GBA1 gene. The entire GBA1 gene has rarely been studied in a large cohort from a single population. The objective of this study was to assess the entire GBA1 gene in Parkinson's disease from a single large population. METHODS: The GBA1 gene was assessed in 3402 Dutch Parkinson's disease patients using...

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Identifiers

PMID: 32618053
DOI: 10.1002/mds.28112
PMCID: PMC7540512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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