Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two multidrug-resistance (ABCB1) gene polymorphisms as prognostic parameters in women with ovarian cancer.

Anticancer research - 1 Sept 2010

Grimm Christoph, Polterauer Stephan, Zeillinger Robert, Tong Dan, Heinze Georg, Wolf Andrea, Natter Camilla, Reinthaller Alexander, Hefler Lukas A

Abstract excerpt

BACKGROUND: The transport protein P-glycoprotein, which is encoded by the multidrug-resistance ABCB1 gene, is crucially involved in the export of taxanes and other cytotoxic substances out of the cell. Treatment response to paclitaxel has been shown to correlate with ABCB1 gene polymorphisms. Data regarding the prognostic value of ABCB1 gene polymorphisms in ovarian cancer patients is conflicting. MATERIALS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Drug Resistance, Neoplasm

Share to Kaplan-Meier Estimate

Share to Neoplasm Staging

Share to Ovarian Neoplasms

Share to Prognosis

Source

Identifiers

PMID: 20944127

Genes

ABCB1

Variants

rs2032582
rs2032582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two multidrug-resistance (ABCB1) gene polymorphisms as prognostic parameters in women with ovarian cancer.PMID 20944127Read ↗

ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas.Semantic proximity Read ↗

mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy.Semantic proximity Read ↗

Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer.Semantic proximity Read ↗

Polymorphisms of ABCB1, CYP3A4 and CYP3A5 Genes in Ovarian Cancer and Treatment Response in Poles.Semantic proximity Read ↗

Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients.Semantic proximity Read ↗

ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/carboplatin chemotherapy.Semantic proximity Read ↗

Predictive value of ABCB1 polymorphisms G2677T/A, C3435T, and their haplotype in small cell lung cancer patients treated with chemotherapy.Semantic proximity Read ↗

Prognostic Value of Two Polymorphisms, rs1045642 and rs1128503, in ABCB1 Following Taxane-based Chemotherapy: A Meta-Analysis.Semantic proximity Read ↗

Multidrug Resistance Gene-1 Is a Useful Predictor of Paclitaxel-Based Chemotherapy for Patients with Ovarian CancerSemantic proximity Read ↗

Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients.Semantic proximity Read ↗

ABCB1 gene polymorphisms and response to chemotherapy in breast cancer patients: A meta-analysis.Semantic proximity Read ↗

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.