Article
ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.
Journal of the National Cancer Institute - 1 Jul 2014
Hedditch Ellen L, Gao Bo, Russell Amanda J, Lu Yi, Emmanuel Catherine, Beesley Jonathan, Johnatty Sharon E, Chen Xiaoqing, Harnett Paul, George Joshy, Williams Rebekka T, Flemming Claudia, Lambrechts Diether, Despierre Evelyn, Lambrechts Sandrina, Vergote Ignace, Karlan Beth, Lester Jenny, Orsulic Sandra, Walsh Christine, Fasching Peter, Beckmann Matthias W, Ekici Arif B, Hein Alexander, Matsuo Keitaro, Hosono Satoyo, Nakanishi Toru, Yatabe Yasushi, Pejovic Tanja, Bean Yukie, Heitz Florian, Harter Philipp, du Bois Andreas, Schwaab Ira, Hogdall Estrid, Kjaer Susan K, Jensen Allan, Hogdall Claus, Lundvall Lene, Engelholm Svend Aage, Brown Bob, Flanagan James, Metcalf Michelle D, Siddiqui Nadeem, Sellers Thomas, Fridley Brooke, Cunningham Julie, Schildkraut Joellen, Iversen Ed, Weber Rachel P, Berchuck Andrew, Goode Ellen, Bowtell David D, Chenevix-Trench Georgia, deFazio Anna, Norris Murray D, MacGregor Stuart, Haber Michelle, Henderson Michelle J
Abstract excerpt
BACKGROUND: ATP-binding cassette (ABC) transporters play various roles in cancer biology and drug resistance, but their association with outcomes in serous epithelial ovarian cancer (EOC) is unknown. METHODS: The relationship between clinical outcomes and ABC transporter gene expression in two independent cohorts of high-grade serous EOC tumors was assessed with real-time quantitative polymerase chain reaction,...
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