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Article

Cell line-dependent variability in HIV activation employing DNMT inhibitors

13 Oct 2010

Abstract excerpt

Long-lived reservoirs of Human Immunodeficiency Virus (HIV) latently infected cells present the main barrier to a cure for HIV infection. Much interest has focused on identifying strategies to activate HIV, which would be used together with antiretrovirals to attack reservoirs. Several HIV activating agents, including Tumor Necrosis Factor alpha (TNFα) and other agents that activate via NF-kB are not fully...

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PMID: 20942961
DOI: 10.1186/1743-422x-7-266

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