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Article

NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption.

European journal of clinical pharmacology - 1 Feb 2011

Kim Sang-Heon, Kim Sang-Hoon, Yoon Ho Joo, Shin Dong Ho, Park Sung Soo, Kim Youn-Seup, Park Jae-Seuk, Jee Young Koo

Abstract excerpt

PURPOSE: It has been suggested that drug-metabolizing enzymes might play important roles in the development of anti-tuberculosis drug (ATD)-induced maculopapular eruption (MPE), as in ATD-induced hepatitis. We investigated the associations between the genetic polymorphisms of drug-metabolizing enzymes and ATD-induced MPE. METHODS: We enrolled 62 patients with ATD-induced MPE (mean age 47.2 ± 19.0, male 59.7%) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20941486
DOI: 10.1007/s00228-010-0912-4

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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