Article
Insulin resistance and low-density apolipoprotein B-associated lipoviral particles in hepatitis C virus genotype 1 infection.
Gut - 1 May 2011
Bridge Simon H, Sheridan David A, Felmlee Daniel J, Nielsen Søren U, Thomas Howard C, Taylor-Robinson Simon D, Neely R Dermot G, Toms Geoffrey L, Bassendine Margaret F
Abstract excerpt
BACKGROUND: The density of hepatitis C virus (HCV) in plasma is heterogeneous but the factors which influence this are poorly understood. Evidence from animal models and cell culture suggest that low-density apolipoprotein B (apoB)-associated HCV lipoviral particles (LVP) are more infectious than high-density HCV. Objective To measure LVP in patients with chronic hepatitis C genotype 1 (CHC-G1) and examine...
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