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Genotoxicity evaluation of sesamin and episesamin.

Mutation research - 3 Feb 2011

Hori Hisako, Takayanagi Tomomi, Kamada Yoko, Shimoyoshi Satomi, Ono Yoshiko, Kitagawa Yoshinori, Shibata Hiroshi, Nagao Minako, Fujii Wataru, Sakakibara Yutaka

Abstract excerpt

Sesamin is a major lignan that is present in sesame seeds and oil. Sesamin is partially converted to its stereoisomer, episesamin, during the refining process of non-roasted sesame seed oil. We evaluated the genotoxicity of these substances through the following tests: a bacterial reverse mutation assay (Ames test), a chromosomal aberration test in cultured Chinese hamster lung cells (CHL/IU), a bone marrow...

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PMID: 20937410
DOI: 10.1016/j.mrgentox.2010.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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