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Article

A novel functional DEC1 promoter polymorphism -249T>C reduces risk of squamous cell carcinoma of the head and neck.

Carcinogenesis - 1 Dec 2010

Huang Yu-Jing, Niu Jiangong, Wei Sheng, Yin Ming, Liu Zhensheng, Wang Li-E, Sturgis Erich M, Wei Qingyi

Abstract excerpt

Human DEC1 (deleted in esophageal cancer 1) gene is located on chromosome 9q, a region frequently deleted in various types of human cancers, including squamous cell carcinoma of the head and neck (SCCHN). However, only one epidemiological study has evaluated the association between DEC1 polymorphisms and cancer risk. In this hospital-based case-control study, four potentially functional single-nucleotide...

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Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to HCT116 Cells

Share to Head and Neck Neoplasms

Share to Promoter Regions, Genetic

Share to Tumor Suppressor Proteins

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Identifiers

PMID: 20935061
DOI: 10.1093/carcin/bgq198
PMCID: PMC2994282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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