Article
Genetic variants of C1orf10 and risk of esophageal squamous cell carcinoma in a Chinese population.
Cancer science - 1 Sept 2009
Zhang Wei, Chen Xiabin, Luo Aiping, Lin Dongxin, Tan Wen, Liu Zhihua
Abstract excerpt
Chromosome 1 open reading frame 10 (C1orf10) is either down-regulated or absent in esophageal squamous cell carcinoma (ESCC) tissues compared to its corresponding normal counterparts, and it is involved in heat shock and ethanol response and is expected to protect esophageal epithelium from damage. In the present study, we sequenced DNA samples from 32 individuals to search for genetic variants in the promoter...
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