Article
Genetics of type 1A diabetes.
Recent progress in hormone research - 1 Jan 2001
Redondo M J, Fain P R, Eisenbarth G S
Abstract excerpt
Type 1A diabetes is an autoimmune disease with genetic and environmental factors contributing to its etiology. Twin studies, family studies, and animal models have helped to elucidate the genetics of autoimmune diabetes. Most of the genetic susceptibility is accounted for by human leukocyte antigen (HLA) alleles. The most-common susceptibility haplotypes are DQA1*0301-DQB1*0302 and DQA1*0501-DQB1*0201....
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