Article
Lysyl oxidase genetic variants and the prognosis of glioma.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Mar 2014
Han Song, Feng Sizhe, Yuan Guanqian, Dong Tao, Gao Dandan, Liang Guobiao, Wei Xuezhong
Abstract excerpt
Lysyl oxidase (LOX) is a copper-dependent amine oxidase that plays important roles in the development and homeostasis of primary brain tumors such as glioma. The aim of this study was to investigate whether polymorphisms in the LOX gene were associated with susceptibility to glioma. We tested two functional polymorphisms of LOX, -22G/C and 473G/A, and compared them between 466 glioma cases and 502 healthy...
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