Article
Social peers rescue autism-relevant sociability deficits in adolescent mice.
Autism research : official journal of the International Society for Autism Research - 1 Feb 2011
Yang Mu, Perry Kayla, Weber Michael D, Katz Adam M, Crawley Jacqueline N
Abstract excerpt
Behavioral therapies are currently the most effective interventions for treating the diagnostic symptoms of autism. We employed a mouse model of autism to evaluate components of behavioral interventions that improve sociability in mice. BTBR T+tf/J (BTBR) is an inbred mouse strain that exhibits prominent behavioral phenotypes with face validity to all three diagnostic symptom categories of autism, including...
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