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Article

Ccm1 regulates microvascular morphogenesis during angiogenesis.

Journal of vascular research - 1 Jan 2011

Liu Huiling, Rigamonti Daniele, Badr Ahmed, Zhang Jun

Abstract excerpt

Cerebral cavernous malformations (CCMs) are characterized by abnormally dilated intracranial capillaries that have a propensity to bleed. The development of some CCMs in humans has been attributed to mutations in CCM1 and CCM2 genes. In animal models, major cardiovascular defects caused by both gene mutations have been observed. However, the effects of the loss of Ccm function on the microvasculature in animal...

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Source

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Identifiers

PMID: 20926893
DOI: 10.1159/000316851
PMCID: PMC3219476

Genes

CCM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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