Article
Multiple meningioma with different grades of malignancy: case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics.
Pathology, research and practice - 15 Jan 2011
Mocker Kristin, Holland Heidrun, Ahnert Peter, Schober Ralf, Bauer Manfred, Kirsten Holger, Koschny Ronald, Meixensberger Jürgen, Krupp Wolfgang
Abstract excerpt
Multiple meningiomas with synchronous tumor lesions represent only 1-9% of all meningiomas and usually show a uniform histology. The simultaneous occurrence of different grades of malignancy in these nodules is observed in only one third of multiple meningiomas. We report a case of a sporadic multiple meningioma presenting with different histopathological grades (WHO I and II). The tumor genome of both nodules...
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