Article
Type I plasminogen activator inhibitor 4G allele frequency is associated with chronic venous insufficiency.
The Journal of international medical research - 1 Jan 2000
Katrancioglu N, Manduz S, Ozen F, Yilmaz M Birhan, Karahan O, Ozdemir O, Berkan O
Abstract excerpt
Chronic venous insufficiency (CVI) is a common disease associated with poor quality of life. Genetic polymorphisms causing coagulation abnormalities may account for some of the CVI pathogenesis. Type I plasminogen activator inhibitor (PAI-1) is responsible for fibrinolytic system regulation, and plasma levels of PAI-1 are strongly correlated with PAI-1 4G/5G gene polymorphism. The association between PAI-1 4G/5G...
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