Article
Monitoring of malaria parasite resistance to chloroquine and sulphadoxine-pyrimethamine in the Solomon Islands by DNA microarray technology.
Malaria journal - 6 Oct 2010
Ballif Marie, Hii Jeffrey, Marfurt Jutta, Crameri Andreas, Fafale Adam, Felger Ingrid, Beck Hans-Peter, Genton Blaise
Abstract excerpt
BACKGROUND: Little information is available on resistance to anti-malarial drugs in the Solomon Islands (SI). The analysis of single nucleotide polymorphisms (SNPs) in drug resistance associated parasite genes is a potential alternative to classical time- and resource-consuming in vivo studies to monitor drug resistance. Mutations in pfmdr1 and pfcrt were shown to indicate chloroquine (CQ) resistance, mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
