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Article

Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics

29 Sept 2010

Abstract excerpt

BACKGROUND: The Limbal epithelial crypt (LEC) is a solid cord of cells, approximately 120 microns long. It arises from the undersurface of interpalisade rete ridges of the limbal palisades of Vogt and extends deeper into the limbal stroma parallel or perpendicular to the palisade. There are up to 6 or 7 such LEC, variably distributed along the limbus in each human eye. Morphological and immunohistochemical...

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PMID: 20920242
DOI: 10.1186/1471-2164-11-526

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