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Article

Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions.

Investigative ophthalmology & visual science - 1 Nov 2009

Utheim Tor P, Raeder Sten, Olstad Ole K, Utheim Øygunn A, de La Paz Maria, Cheng Robert, Huynh Trang T, Messelt Edward, Roald Borghild, Lyberg Torstein

Abstract excerpt

PURPOSE: To investigate whether human limbal epithelial cells (HLECs) derived from various regions of the limbus exhibit differences in gene expression and epithelial characteristics. METHODS: HLECs were derived from explants taken from the superior, nasal, inferior, and temporal limbus and cultured for 21 days. Whole genome transcript profiling was performed with a gene microarray. The microarray results were...

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Source

Identifiers

PMID: 19578011
DOI: 10.1167/iovs.08-2884

Genes

ABCG2
OSR2
RHOU
TRIM36

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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