Article
Effects of glutathione S-transferase M1 andT1 deletions on bipolar disorder risk among a Tunisian population.
Gene - 5 Apr 2017
Chbili Chahra, Elouaer Ahlem, Fathallah Neila, Nouira Manel, Jrad Besma Bel Hadj, Gaha Lotfi, Saguem Saad
Abstract excerpt
Glutathione S-transferases (GSTs) enzymes are involved in the detoxification of several endogenous and exogenous substances. In this study, we evaluated the effects of two glutathione S-transferase polymorphisms, (GSTM1 and GSTT1) on bipolar disorder (BPD) risk susceptibility in a Tunisian population. These polymorphisms were analyzed in 229 healthy subjects and 109 patients with BPD, using a polymerase chain...
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