Article
Glutathione S-transferase M1 and T1 genes deletion polymorphisms and risk of developing essential hypertension: a case-control study in Burkina Faso population (West Africa).
BMC medical genetics - 19 Mar 2020
Sombié Herman Karim, Sorgho Abel Pegdwendé, Kologo Jonas Koudougou, Ouattara Abdoul Karim, Yaméogo Sakinata, Yonli Albert Théophane, Djigma Florencia Wendkuuni, Tchelougou Daméhan, Somda Dogfounianalo, Kiendrébéogo Isabelle Touwendpoulimdé, Bado Prosper, Nagalo Bolni Marius, Nagabila Youssoufou, Adoko Enagnon Tiémoko Herman Donald, Zabsonré Patrice, Millogo Hassanata, Simporé Jacques
Abstract excerpt
BACKGROUND: Glutathione S-transferases play a key role in the detoxification of persistent oxidative stress products which are one of several risks factors that may be associated with many types of disease processes such as cancer, diabetes, and hypertension. In the present study, we characterize the null genotypes of GSTM1 and GSTT1 in order to investigate the association between them and the risk of developing...
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