Article
JAK2 V617F and MPL W515L/K mutations in Korean patients with essential thrombocythemia.
The Korean journal of laboratory medicine - 1 Oct 2010
Kim Hee-Jung, Jang Ja-Hyun, Yoo Eun-Hyung, Kim Hee-Jin, Ki Chang-Seok, Kim Jong-Won, Kim Sun-Hee
Abstract excerpt
JAK2 V617F and MPL W515L/K mutations have been reported in approximately 50% and 5% of the patients with essential thrombocythemia (ET), respectively. We investigated the frequency of MPL W515L/K mutations in a series of consecutive patients with ET and post-essential thrombocythemia myelofibrosis (post-ET MF). The study subjects were 63 patients diagnosed either with ET (N=59) or post-ET MF (N=4) at our...
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