Article
Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis.
Lancet (London, England) - 23 Oct 2010
Williams Nigel M, Zaharieva Irina, Martin Andrew, Langley Kate, Mantripragada Kiran, Fossdal Ragnheidur, Stefansson Hreinn, Stefansson Kari, Magnusson Pall, Gudmundsson Olafur O, Gustafsson Omar, Holmans Peter, Owen Michael J, O'Donovan Michael, Thapar Anita
Abstract excerpt
BACKGROUND: Large, rare chromosomal deletions and duplications known as copy number variants (CNVs) have been implicated in neurodevelopmental disorders similar to attention-deficit hyperactivity disorder (ADHD). We aimed to establish whether burden of CNVs was increased in ADHD, and to investigate whether identified CNVs were enriched for loci previously identified in autism and schizophrenia. METHODS: We...
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