Article
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3.
The American journal of psychiatry - 1 Feb 2012
Williams Nigel M, Franke Barbara, Mick Eric, Anney Richard J L, Freitag Christine M, Gill Michael, Thapar Anita, O'Donovan Michael C, Owen Michael J, Holmans Peter, Kent Lindsey, Middleton Frank, Zhang-James Yanli, Liu Lu, Meyer Jobst, Nguyen Thuy Trang, Romanos Jasmin, Romanos Marcel, Seitz Christiane, Renner Tobias J, Walitza Susanne, Warnke Andreas, Palmason Haukur, Buitelaar Jan, Rommelse Nanda, Vasquez Alejandro Arias, Hawi Ziarih, Langley Kate, Sergeant Joseph, Steinhausen Hans-Christoph, Roeyers Herbert, Biederman Joseph, Zaharieva Irina, Hakonarson Hakon, Elia Josephine, Lionel Anath C, Crosbie Jennifer, Marshall Christian R, Schachar Russell, Scherer Stephen W, Todorov Alexandre, Smalley Susan L, Loo Sandra, Nelson Stanley, Shtir Corina, Asherson Philip, Reif Andreas, Lesch Klaus-Peter, Faraone Stephen V
Abstract excerpt
OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a common, highly heritable psychiatric disorder. Because of its multifactorial etiology, however, identifying the genes involved has been difficult. The authors followed up on recent findings suggesting that rare copy number variants (CNVs) may be important for ADHD etiology. METHOD: The authors performed a genome-wide analysis of large, rare CNVs (<1%...
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