Article
Mutational and bioinformatic analysis of haloarchaeal lipobox-containing proteins.
Archaea (Vancouver, B.C.) - 16 Sept 2010
Storf Stefanie, Pfeiffer Friedhelm, Dilks Kieran, Chen Zhong Qiang, Imam Saheed, Pohlschröder Mechthild
Abstract excerpt
A conserved lipid-modified cysteine found in a protein motif commonly referred to as a lipobox mediates the membrane anchoring of a subset of proteins transported across the bacterial cytoplasmic membrane via the Sec pathway. Sequenced haloarchaeal genomes encode many putative lipoproteins and recent studies have confirmed the importance of the conserved lipobox cysteine for signal peptide processing of three...
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