Article
LonB Protease Is a Novel Regulator of Carotenogenesis Controlling Degradation of Phytoene Synthase in Haloferax volcanii.
Journal of proteome research - 2 Mar 2018
Cerletti Micaela, Paggi Roberto, Troetschel Christian, Ferrari María Celeste, Guevara Carina Ramallo, Albaum Stefan, Poetsch Ansgar, De Castro Rosana
Abstract excerpt
The membrane protease LonB is an essential protein in the archaeon Haloferax volcanii and globally impacts its physiology. However, natural substrates of the archaeal Lon protease have not been identified. The whole proteome turnover was examined in a H. volcanii LonB mutant under reduced and physiological protease levels. LC-MS/MS combined with stable isotope labeling was applied for the...
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