Article
Low-pass sequencing for microbial comparative genomics.
BMC genomics - 12 Jan 2004
Goo Young Ah, Roach Jared, Glusman Gustavo, Baliga Nitin S, Deutsch Kerry, Pan Min, Kennedy Sean, DasSarma Shiladitya, Ng Wailap Victor, Hood Leroy
Abstract excerpt
BACKGROUND: We studied four extremely halophilic archaea by low-pass shotgun sequencing: (1) the metabolically versatile Haloarcula marismortui; (2) the non-pigmented Natrialba asiatica; (3) the psychrophile Halorubrum lacusprofundi and (4) the Dead Sea isolate Halobaculum gomorrense. Approximately one thousand single pass genomic sequences per genome were obtained. The data were analyzed by comparative genomic...
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