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Article

Towards a systems approach in the genetic analysis of archaea: Accelerating mutant construction and phenotypic analysis in Haloferax volcanii.

Archaea (Vancouver, B.C.) - 23 Dec 2010

Blaby Ian K, Phillips Gabriela, Blaby-Haas Crysten E, Gulig Kevin S, El Yacoubi Basma, de Crécy-Lagard Valérie

Abstract excerpt

With the availability of a genome sequence and increasingly sophisticated genetic tools, Haloferax volcanii is becoming a model for both Archaea and halophiles. In order for H. volcanii to reach a status equivalent to Escherichia coli, Bacillus subtilis, or Saccharomyces cerevisiae, a gene knockout collection needs to be constructed in order to identify the archaeal essential gene set and enable systematic...

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Identifiers

PMID: 21234384
DOI: 10.1155/2010/426239
PMCID: PMC3017900

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