Article
[Analysis of population stratification using random SNPs in genome-wide association studies].
Yi chuan = Hereditas - 1 Sept 2010
Cao Zong-Fu, Ma Chuan-Xiang, Wang Lei, Cai Bin
Abstract excerpt
Since population genetic STRUCTURE can increase false-positive rate in genome-wide association studies (GWAS) for complex diseases, the effect of population stratification should be taken into account in GWAS. However, the effect of randomly selected SNPs in population stratification analysis is underdetermined. In this study, based on the genotype data generated on Genome-Wide Human SNP Array 6.0 from unrelated...
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