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Article

A panel of ancestry informative markers to estimate and correct potential effects of population stratification in Han Chinese.

European journal of human genetics : EJHG - 1 Feb 2014

Qin Pengfei, Li Zhiqiang, Jin Wenfei, Lu Dongsheng, Lou Haiyi, Shen Jiawei, Jin Li, Shi Yongyong, Xu Shuhua

Abstract excerpt

Population stratification acts as a confounding factor in genetic association studies and may lead to false-positive or false-negative results. Previous studies have analyzed the genetic substructures in Han Chinese population, the largest ethnic group in the world comprising ∼20% of the global human population. In this study, we examined 5540 Han Chinese individuals with about 1 million single-nucleotide...

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PMID: 23714748
DOI: 10.1038/ejhg.2013.111
PMCID: PMC3895631

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