Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[GATA1 analysis in myeloproliferative disorders associated to trisomy 21].

Anales de pediatria (Barcelona, Spain : 2003) - 1 Jan 2011

Fuster Soler J L, Norton A, Galera Miñarro A, Bermúdez Cortés M, Llinares Riestra M E, Ortuño Giner F

Abstract excerpt

INTRODUCTION: Neonatal transient myeloproliferative disorder and acute megakaryoblastic leukaemia of Down syndrome are considered different manifestations of the same disease. In most cases, transient myeloproliferative disorders require no treatment, while acute megakaryoblastic leukaemia of Down's syndrome is characterised by an increased sensitivity to chemotherapy and its treatment should be adapted with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Down Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GATA1 Transcription Factor

Share to GATA1 gene

Share to Infant

Share to Infant, Newborn

Share to Mutation

Share to Myeloproliferative Disorders

Source

Identifiers

PMID: 20870473
DOI: 10.1016/j.anpedi.2010.08.012

Genes

GATA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[GATA1 analysis in myeloproliferative disorders associated to trisomy 21].PMID 20870473Read ↗

Transient abnormal myelopoiesis in a cytogenetically normal neonate.Semantic proximity Read ↗

[GATA1-mutation associated leukemia in children with trisomy 21 mosaic].Semantic proximity Read ↗

Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children.Semantic proximity Read ↗

GATA1 mutations in Down syndrome: implications for biology and diagnosis of children with transient myeloproliferative disorder and acute megakaryoblastic leukemia.Semantic proximity Read ↗

GATA1 mutation and trisomy 21 are required only in haematopoietic cells for development of transient myeloproliferative disorder.Semantic proximity Read ↗

Molecular insights into Down syndrome-associated leukemia.Semantic proximity Read ↗

Transient Abnormal Myelopoiesis and AML in Down Syndrome: an UpdateSemantic proximity Read ↗

Acute megakaryoblastic leukemia with a novel GATA1 mutation in a second trimester stillborn fetus with trisomy 21.Semantic proximity Read ↗

Acute megakaryoblastic leukemia without GATA1 mutation after transient myeloproliferative disorder in an infant without Down syndrome.Semantic proximity Read ↗

Transient abnormal myelopoiesis in neonates: GATA get the diagnosis.Semantic proximity Read ↗

Detection of a clone-specific GATA1 mutation to monitor treatment response and involvement of a monozygotic twin in myeloid leukemia of Down syndrome.Semantic proximity Read ↗

GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.