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Network-Based Analysis of Affected Biological Processes in Type 2 Diabetes Models

6 Jun 2007

Abstract excerpt

Type 2 diabetes mellitus is a complex disorder associated with multiple genetic, epigenetic, developmental, and environmental factors. Animal models of type 2 diabetes differ based on diet, drug treatment, and gene knockouts, and yet all display the clinical hallmarks of hyperglycemia and insulin resistance in peripheral tissue. The recent advances in gene-expression microarray technologies present an...

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PMID: 17571924
DOI: 10.1371/journal.pgen.0030096

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