Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A model for damage load and its implications for the evolution of bacterial aging.

PLoS genetics - 26 Aug 2010

Chao Lin

Abstract excerpt

Deleterious mutations appearing in a population increase in frequency until stopped by natural selection. The ensuing equilibrium creates a stable frequency of deleterious mutations or the mutational load. Here I develop the comparable concept of a damage load, which is caused by harmful non-heritable changes to the phenotype. A damage load also ensues when the increase of damage is opposed by selection. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to DNA Damage
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Models, Theoretical

Share to Mutation

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20865171
DOI: 10.1371/journal.pgen.1001076
PMCID: PMC2928801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A model for damage load and its implications for the evolution of bacterial aging.PMID 20865171Read ↗

Age structure landscapes emerge from the equilibrium between aging and rejuvenation in bacterial populations.Semantic proximity Read ↗

On the evolutionary origin of aging.Semantic proximity Read ↗

The Muller's Ratchet and Aging.Semantic proximity Read ↗

Nonlethal deleterious mutation-induced stress accelerates bacterial aging.Semantic proximity Read ↗

Phenotypic plasticity and effects of selection on cell division symmetry in Escherichia coli.Semantic proximity Read ↗

The Double Code Hypothesis of AgeingSemantic proximity Read ↗

Mutation and epimutation load in haploid and diploid life forms.Semantic proximity Read ↗

Senescence in a bacterium with asymmetric division.Semantic proximity Read ↗

Genetic and epigenetic Muller's ratchet as a mechanism of frailty and morbidity during aging: a demographic genetic model.Semantic proximity Read ↗

Muller’s ratchet as a mechanism of frailty and multimorbiditySemantic proximity Read ↗

Unicellular life balances asymmetric allocation and repair of somatic damage representing the origin of r/K selectionSemantic proximity Read ↗

The origin of the logic of adaptive mutations: standing by to grow again.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.