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Article

Involvement of toll-like receptor 4 in alveolar bone loss and glucose homeostasis in experimental periodontitis.

Journal of periodontal research - 1 Feb 2011

Watanabe K, Iizuka T, Adeleke A, Pham L, Shlimon A E, Yasin M, Horvath P, Unterman T G

Abstract excerpt

BACKGROUND AND OBJECTIVE: There is general agreement that certain fatty acids and lipopolysaccharides (LPS) promote inflammation through toll-like receptor 4 (TLR4), and that inflammation promotes insulin resistance. We therefore hypothesized that mice with periodontitis and a TLR4 loss-of-functi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20860587
DOI: 10.1111/j.1600-0765.2010.01304.x
PMCID: PMC4569008

Genes

TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20860587-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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