Article
Periodontitis as a novel contributor of adipose tissue inflammation promotes insulin resistance in a rat model.
Journal of periodontology - 1 Nov 2013
Su Yuan, Wang Dan, Xuan Dongying, Ni Jia, Luo Shigao, Xie Baoyi, Zhang Jincai
Abstract excerpt
BACKGROUND: Recent studies have indicated that the chronic low-grade inflammation induced by periodontitis is related to obesity and type 2 diabetes mellitus. The purpose of this study is to investigate the effects of periodontitis on obesity-related adipose tissue inflammation and subsequent systemic insulin resistance in a rat model. METHODS: Thirty-two rats were divided into four groups of eight: 1) obese rats...
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