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Article

Biosynthetic regulation and intracellular transport of phosphatidylserine in mammalian cells.

Journal of biochemistry - 1 Apr 2003

Kuge Osamu, Nishijima Masahiro

Abstract excerpt

In mammalian cells, phosphatidylserine (PtdSer) is synthesized through the action of the endoplasmic reticulum enzymes, PtdSer synthase 1 and 2, and the decarboxylation of PtdSer accounts for the majority of phosphatidylethanolamine (PtdEtn) synthesis. PtdSer decarboxylation for PtdEtn formation occurs in the mitochondria. In addition, the transport of PtdSer from the endoplasmic reticulum to the mitochondria is...

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PMID: 12761285
DOI: 10.1093/jb/mvg052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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