Article
CRY2 is associated with rapid cycling in bipolar disorder patients.
PloS one - 9 Sept 2010
Sjöholm Louise K, Backlund Lena, Cheteh Emarndeena Haji, Ek Inger Römer, Frisén Louise, Schalling Martin, Osby Urban, Lavebratt Catharina, Nikamo Pernilla
Abstract excerpt
BACKGROUND: Bipolar disorder patients often display abnormalities in circadian rhythm, and they are sensitive to irregular diurnal rhythms. CRY2 participates in the core clock that generates circadian rhythms. CRY2 mRNA expression in blood mononuclear cells was recently shown to display a marked diurnal variation and to respond to total sleep deprivation in healthy human volunteers. It was also shown that bipolar...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.